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An optimized rapid bisulfite conversion method with high recovery of cell-free DNA

BACKGROUND: Methylation analysis of cell-free DNA is a encouraging tool for tumor diagnosis, monitoring and prognosis. Sensitivity of methylation analysis is a very important matter due to the tiny amounts of cell-free DNA available in plasma. Most current methods of DNA methylation analysis are bas...

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Detalles Bibliográficos
Autores principales: Yi, Shaohua, Long, Fei, Cheng, Juanbo, Huang, Daixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735811/
https://www.ncbi.nlm.nih.gov/pubmed/29258436
http://dx.doi.org/10.1186/s12867-017-0101-4