Radiotherapy enhances natural killer cell cytotoxicity and localization in pre-clinical canine sarcomas and first-in-dog clinical trial

BACKGROUND: We have previously shown that radiotherapy (RT) augments natural killer (NK) functions in pre-clinical models of human and mouse cancers, including sarcomas. Since dogs are an excellent outbred model for immunotherapy studies, we sought to assess RT plus local autologous NK transfer in c...

Descripción completa

Detalles Bibliográficos
Autores principales: Canter, Robert J., Grossenbacher, Steven K., Foltz, Jennifer A., Sturgill, Ian R., Park, Jiwon S., Luna, Jesus I., Kent, Michael S., Culp, William T. N., Chen, Mingyi, Modiano, Jaime F., Monjazeb, Arta M., Lee, Dean A., Murphy, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735903/
https://www.ncbi.nlm.nih.gov/pubmed/29254507
http://dx.doi.org/10.1186/s40425-017-0305-7

Ejemplares similares

Ejemplares similares