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Renal allograft rejection, lymphocyte infiltration, and de novo donor-specific antibodies in a novel model of non-adherence to immunosuppressive therapy

BACKGROUND: Non-adherence has been associated with reduced graft survival. The aim of this study was to investigate the immunological mechanisms underlying chronic renal allograft rejection using a model of non-adherence to immunosuppressive therapy. We used a MHC (major histocompatibility complex)...

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Detalles Bibliográficos
Autores principales: Kühne, Louisa, Jung, Bettina, Poth, Helen, Schuster, Antonia, Wurm, Simone, Ruemmele, Petra, Banas, Bernhard, Bergler, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735914/
https://www.ncbi.nlm.nih.gov/pubmed/29258420
http://dx.doi.org/10.1186/s12865-017-0236-6

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