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Passive Double-Sensory Evoked Coherence Correlates with Long-Term Memory Capacity

HIGHLIGHTS: Memory correlates with the difference between single and double-sensory evoked steady-state coherence in the gamma range (ΔC). The correlation is most pronounced for the anterior brain region (ΔC(A)). The correlation is not driven by birth size, education, speed of processing, or intelli...

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Autores principales: Horwitz, Anna, Mortensen, Erik L., Osler, Merete, Fagerlund, Birgitte, Lauritzen, Martin, Benedek, Krisztina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735981/
https://www.ncbi.nlm.nih.gov/pubmed/29311868
http://dx.doi.org/10.3389/fnhum.2017.00598
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author Horwitz, Anna
Mortensen, Erik L.
Osler, Merete
Fagerlund, Birgitte
Lauritzen, Martin
Benedek, Krisztina
author_facet Horwitz, Anna
Mortensen, Erik L.
Osler, Merete
Fagerlund, Birgitte
Lauritzen, Martin
Benedek, Krisztina
author_sort Horwitz, Anna
collection PubMed
description HIGHLIGHTS: Memory correlates with the difference between single and double-sensory evoked steady-state coherence in the gamma range (ΔC). The correlation is most pronounced for the anterior brain region (ΔC(A)). The correlation is not driven by birth size, education, speed of processing, or intelligence. The sensitivity of ΔC(A) for detecting low memory capacity is 90%. Cerebral rhythmic activity and oscillations are important pathways of communication between cortical cell assemblies and may be key factors in memory. We asked whether memory performance is related to gamma coherence in a non-task sensory steady-state stimulation. We investigated 40 healthy males born in 1953 who were part of a Danish birth cohort study. Coherence was measured in the gamma range in response to a single-sensory visual stimulation (36 Hz) and a double-sensory combined audiovisual stimulation (auditive: 40 Hz; visual: 36 Hz). The individual difference in coherence (ΔC) between the bimodal and monomodal stimulation was calculated for each subject and used as the main explanatory variable. ΔC in total brain were significantly negatively correlated with long-term verbal recall. This correlation was pronounced for the anterior region. In addition, the correlation between ΔC and long-term memory was robust when controlling for working memory, as well as a wide range of potentially confounding factors, including intelligence, length of education, speed of processing, visual attention and executive function. Moreover, we found that the difference in anterior coherence (ΔC(A)) is a better predictor of memory than power in multivariate models. The sensitivity of ΔC(A) for detecting low memory capacity is 92%. Finally, ΔC(A) was also associated with other types of memory: verbal learning, visual recognition, and spatial memory, and these additional correlations were also robust enough to control for a range of potentially confounding factors. Thus, the ΔC is a predictor of memory performance may be useful in cognitive neuropsychological testing.
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spelling pubmed-57359812018-01-08 Passive Double-Sensory Evoked Coherence Correlates with Long-Term Memory Capacity Horwitz, Anna Mortensen, Erik L. Osler, Merete Fagerlund, Birgitte Lauritzen, Martin Benedek, Krisztina Front Hum Neurosci Neuroscience HIGHLIGHTS: Memory correlates with the difference between single and double-sensory evoked steady-state coherence in the gamma range (ΔC). The correlation is most pronounced for the anterior brain region (ΔC(A)). The correlation is not driven by birth size, education, speed of processing, or intelligence. The sensitivity of ΔC(A) for detecting low memory capacity is 90%. Cerebral rhythmic activity and oscillations are important pathways of communication between cortical cell assemblies and may be key factors in memory. We asked whether memory performance is related to gamma coherence in a non-task sensory steady-state stimulation. We investigated 40 healthy males born in 1953 who were part of a Danish birth cohort study. Coherence was measured in the gamma range in response to a single-sensory visual stimulation (36 Hz) and a double-sensory combined audiovisual stimulation (auditive: 40 Hz; visual: 36 Hz). The individual difference in coherence (ΔC) between the bimodal and monomodal stimulation was calculated for each subject and used as the main explanatory variable. ΔC in total brain were significantly negatively correlated with long-term verbal recall. This correlation was pronounced for the anterior region. In addition, the correlation between ΔC and long-term memory was robust when controlling for working memory, as well as a wide range of potentially confounding factors, including intelligence, length of education, speed of processing, visual attention and executive function. Moreover, we found that the difference in anterior coherence (ΔC(A)) is a better predictor of memory than power in multivariate models. The sensitivity of ΔC(A) for detecting low memory capacity is 92%. Finally, ΔC(A) was also associated with other types of memory: verbal learning, visual recognition, and spatial memory, and these additional correlations were also robust enough to control for a range of potentially confounding factors. Thus, the ΔC is a predictor of memory performance may be useful in cognitive neuropsychological testing. Frontiers Media S.A. 2017-12-14 /pmc/articles/PMC5735981/ /pubmed/29311868 http://dx.doi.org/10.3389/fnhum.2017.00598 Text en Copyright © 2017 Horwitz, Mortensen, Osler, Fagerlund, Lauritzen and Benedek. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Horwitz, Anna
Mortensen, Erik L.
Osler, Merete
Fagerlund, Birgitte
Lauritzen, Martin
Benedek, Krisztina
Passive Double-Sensory Evoked Coherence Correlates with Long-Term Memory Capacity
title Passive Double-Sensory Evoked Coherence Correlates with Long-Term Memory Capacity
title_full Passive Double-Sensory Evoked Coherence Correlates with Long-Term Memory Capacity
title_fullStr Passive Double-Sensory Evoked Coherence Correlates with Long-Term Memory Capacity
title_full_unstemmed Passive Double-Sensory Evoked Coherence Correlates with Long-Term Memory Capacity
title_short Passive Double-Sensory Evoked Coherence Correlates with Long-Term Memory Capacity
title_sort passive double-sensory evoked coherence correlates with long-term memory capacity
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735981/
https://www.ncbi.nlm.nih.gov/pubmed/29311868
http://dx.doi.org/10.3389/fnhum.2017.00598
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