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Nicotinic alpha 7 receptor agonists EVP-6124 and BMS-933043, attenuate scopolamine-induced deficits in visuo-spatial paired associates learning

Agonists at the nicotinic acetylcholine alpha 7 receptor (nAChR α7) subtype have the potential to treat cognitive deficits in patients with Alzheimer’s disease (AD) or schizophrenia. Visuo-spatial paired associates learning (vsPAL) is a task that has been shown to reliably predict conversion from mi...

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Detalles Bibliográficos
Autores principales: Weed, Michael R., Polino, Joseph, Signor, Laura, Bookbinder, Mark, Keavy, Deborah, Benitex, Yulia, Morgan, Daniel G., King, Dalton, Macor, John E., Zaczek, Robert, Olson, Richard, Bristow, Linda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736175/
https://www.ncbi.nlm.nih.gov/pubmed/29261656
http://dx.doi.org/10.1371/journal.pone.0187609