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Endotheliopathy is associated with higher levels of cell-free DNA following major trauma: A prospective observational study
BACKGROUND: Cell free deoxyribonucleic acid (cfDNA) has been proposed as a biomarker of secondary complications following trauma. Raised thrombomodulin and syndecan-1 levels have been used to indicate endotheliopathy, and are associated with inflammation, coagulopathy, and mortality. The current stu...
Autores principales: | Naumann, David N., Hazeldine, Jon, Dinsdale, Robert J., Bishop, Jon R., Midwinter, Mark J., Harrison, Paul, Hutchings, Sam D., Lord, Janet M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736230/ https://www.ncbi.nlm.nih.gov/pubmed/29261771 http://dx.doi.org/10.1371/journal.pone.0189870 |
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