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Improvement of Photoreceptor Targeting via Intravitreal Delivery in Mouse and Human Retina Using Combinatory rAAV2 Capsid Mutant Vectors

PURPOSE: Effective intravitreal gene delivery to cells of the central retina (i.e., photoreceptors) would be of substantial benefit for treating patients with retinal diseases, such as achromatopsia, where retinal detachment from a subretinal may be harmful. Previous studies demonstrated that mutati...

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Detalles Bibliográficos
Autores principales: Reid, Christopher A., Ertel, Kristina J., Lipinski, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736327/
https://www.ncbi.nlm.nih.gov/pubmed/29260200
http://dx.doi.org/10.1167/iovs.17-22281

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