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Study of binding interaction of rivaroxaban with bovine serum albumin using multi-spectroscopic and molecular docking approach
BACKGROUND: Rivaroxaban is a direct inhibitor of coagulation factor Xa and is used for venous thromboembolic disorders. The rivaroxaban interaction with BSA was studied to understand its PK and PD (pharmacokinetics and pharmacokinetics) properties. Multi-spectroscopic studies were used to study the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736510/ https://www.ncbi.nlm.nih.gov/pubmed/29260434 http://dx.doi.org/10.1186/s13065-017-0366-1 |