Mucosal-Associated Invariant T Cell Interactions with Commensal and Pathogenic Bacteria: Potential Role in Antimicrobial Immunity in the Child

Mucosal-associated invariant T (MAIT) cells are unconventional CD3(+)CD161(high) T lymphocytes that recognize vitamin B2 (riboflavin) biosynthesis precursor derivatives presented by the MHC-I related protein, MR1. In humans, their T cell receptor is composed of a Vα7.2-Jα33/20/12 chain, combined wit...

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Detalles Bibliográficos
Autores principales: Ghazarian, Liana, Caillat-Zucman, Sophie, Houdouin, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736530/
https://www.ncbi.nlm.nih.gov/pubmed/29326714
http://dx.doi.org/10.3389/fimmu.2017.01837

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