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Peroxisome proliferator-activated receptor alpha agonist suppresses neovascularization by reducing both vascular endothelial growth factor and angiopoietin-2 in corneal alkali burn

We investigated the effect of a peroxisome proliferator-activated receptor alpha (PPARα) agonist ophthalmic solution in wound healing using a rat corneal alkali burn model. After instillation of a selective agonist of PPARα, fenofibrate, onto the burned cornea, PPARα-positive cells were observed in...

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Detalles Bibliográficos
Autores principales:	Arima, Takeshi, Uchiyama, Masaaki, Nakano, Yuichiro, Nagasaka, Shinya, Kang, Dedong, Shimizu, Akira, Takahashi, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736552/ https://www.ncbi.nlm.nih.gov/pubmed/29259285 http://dx.doi.org/10.1038/s41598-017-18113-3

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