A Novel Cell Line Based Orthotopic Xenograft Mouse Model That Recapitulates Human Hepatoblastoma

Currently, preclinical testing of therapies for hepatoblastoma (HB) is limited to subcutaneous and intrasplenic xenograft models that do not recapitulate the hepatic tumors seen in patients. We hypothesized that injection of HB cell lines into the livers of mice would result in liver tumors that res...

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Detalles Bibliográficos
Autores principales: Woodfield, Sarah E., Shi, Yan, Patel, Roma H., Jin, Jingling, Major, Angela, Sarabia, Stephen F., Starosolski, Zbigniew, Zorman, Barry, Gupta, Siddharth S., Chen, Zhenghu, Ibarra, Aryana M., Bissig, Karl-Dimiter, Ghaghada, Ketan B., Sumazin, Pavel, López-Terrada, Dolores, Vasudevan, Sanjeev A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736579/
https://www.ncbi.nlm.nih.gov/pubmed/29259231
http://dx.doi.org/10.1038/s41598-017-17665-8

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