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Systematic screening of generic drugs for progressive multiple sclerosis identifies clomipramine as a promising therapeutic
The treatment of progressive multiple sclerosis (MS) is unsatisfactory. One reason is that the drivers of disease, which include iron-mediated neurotoxicity, lymphocyte activity, and oxidative stress, are not simultaneously targeted. Here we present a systematic screen to identify generic, orally av...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736601/ https://www.ncbi.nlm.nih.gov/pubmed/29259169 http://dx.doi.org/10.1038/s41467-017-02119-6 |