Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia

Juvenile myelomonocytic leukemia (JMML) is a myeloproliferative disorder of childhood caused by mutations in the Ras pathway. Outcomes in JMML vary markedly from spontaneous resolution to rapid relapse after hematopoietic stem cell transplantation. Here, we hypothesized that DNA methylation patterns...

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Detalles Bibliográficos
Autores principales: Stieglitz, Elliot, Mazor, Tali, Olshen, Adam B., Geng, Huimin, Gelston, Laura C., Akutagawa, Jon, Lipka, Daniel B., Plass, Christoph, Flotho, Christian, Chehab, Farid F., Braun, Benjamin S., Costello, Joseph F., Loh, Mignon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736624/
https://www.ncbi.nlm.nih.gov/pubmed/29259179
http://dx.doi.org/10.1038/s41467-017-02178-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736624/
https://www.ncbi.nlm.nih.gov/pubmed/29259179
http://dx.doi.org/10.1038/s41467-017-02178-9

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