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The after-hours circadian mutant has reduced phenotypic plasticity in behaviors at multiple timescales and in sleep homeostasis

Circadian clock is known to adapt to environmental changes and can significantly influence cognitive and physiological functions. In this work, we report specific behavioral, cognitive, and sleep homeostatic defects in the after hours (Afh) circadian mouse mutant, which is characterized by lengthene...

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Detalles Bibliográficos
Autores principales: Maggi, Silvia, Balzani, Edoardo, Lassi, Glenda, Garcia-Garcia, Celina, Plano, Andrea, Espinoza, Stefano, Mus, Liudmila, Tinarelli, Federico, Nolan, Patrick M., Gainetdinov, Raul R., Balci, Fuat, Nieus, Thierry, Tucci, Valter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736711/
https://www.ncbi.nlm.nih.gov/pubmed/29259298
http://dx.doi.org/10.1038/s41598-017-18130-2