The malignant niche: safe spaces for toxic stem cell marketing

Many tumors are sustained by microenvironments, or niches, that support and protect malignant cells, thus conferring a competitive advantage against both healthy cells and therapeutic interventions (for a brief review, see Yao and Link (Stem Cells 35: 3–8, 2017)). The global industry engaged in the...

Descripción completa

Detalles Bibliográficos
Autor principal: Sipp, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736713/
https://www.ncbi.nlm.nih.gov/pubmed/29302366
http://dx.doi.org/10.1038/s41536-017-0036-x
_version_ 1783287413483765760
author Sipp, Douglas
author_facet Sipp, Douglas
author_sort Sipp, Douglas
collection PubMed
description Many tumors are sustained by microenvironments, or niches, that support and protect malignant cells, thus conferring a competitive advantage against both healthy cells and therapeutic interventions (for a brief review, see Yao and Link (Stem Cells 35: 3–8, 2017)). The global industry engaged in the commercial promotion of unproven and scientifically implausible cell-based “regenerative” therapies has developed a number of self-protective strategies that support its survival and growth in ways that are broadly analogous to the functions of the malignant niche.
format Online
Article
Text
id pubmed-5736713
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-57367132018-01-04 The malignant niche: safe spaces for toxic stem cell marketing Sipp, Douglas NPJ Regen Med Perspective Many tumors are sustained by microenvironments, or niches, that support and protect malignant cells, thus conferring a competitive advantage against both healthy cells and therapeutic interventions (for a brief review, see Yao and Link (Stem Cells 35: 3–8, 2017)). The global industry engaged in the commercial promotion of unproven and scientifically implausible cell-based “regenerative” therapies has developed a number of self-protective strategies that support its survival and growth in ways that are broadly analogous to the functions of the malignant niche. Nature Publishing Group UK 2017-12-19 /pmc/articles/PMC5736713/ /pubmed/29302366 http://dx.doi.org/10.1038/s41536-017-0036-x Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Perspective
Sipp, Douglas
The malignant niche: safe spaces for toxic stem cell marketing
title The malignant niche: safe spaces for toxic stem cell marketing
title_full The malignant niche: safe spaces for toxic stem cell marketing
title_fullStr The malignant niche: safe spaces for toxic stem cell marketing
title_full_unstemmed The malignant niche: safe spaces for toxic stem cell marketing
title_short The malignant niche: safe spaces for toxic stem cell marketing
title_sort malignant niche: safe spaces for toxic stem cell marketing
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736713/
https://www.ncbi.nlm.nih.gov/pubmed/29302366
http://dx.doi.org/10.1038/s41536-017-0036-x
work_keys_str_mv AT sippdouglas themalignantnichesafespacesfortoxicstemcellmarketing
AT sippdouglas malignantnichesafespacesfortoxicstemcellmarketing

Ejemplares similares