Identification of new genes associated to senescent and tumorigenic phenotypes in mesenchymal stem cells

Although human mesenchymal stem cells (hMSCs) are a powerful tool for cell therapy, prolonged culture times result in replicative senescence or acquisition of tumorigenic features. To identify a molecular signature for senescence, we compared the transcriptome of senescent and young hMSCs with norma...

Descripción completa

Detalles Bibliográficos
Autores principales: Medeiros Tavares Marques, Joana Cristina, Cornélio, Déborah Afonso, Nogueira Silbiger, Vivian, Ducati Luchessi, André, de Souza, Sandro, Batistuzzo de Medeiros, Silvia Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736717/
https://www.ncbi.nlm.nih.gov/pubmed/29259202
http://dx.doi.org/10.1038/s41598-017-16224-5

Ejemplares similares

Ejemplares similares