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Successful introduction of Model for End-stage Liver Disease scoring in deceased donor liver transplantation in Korea: analysis of first 1 year experience at a high-volume transplantation center
BACKGROUNDS/AIMS: Model for End-stage Liver Disease (MELD) score was adopted in June 2016 in Korea. METHODS: We analyzed changes in volumes and outcomes of deceased donor liver transplantation (DDLT) for 1 year before and after introduction of MELD scoring at Asan Medical Center. RESULTS: There were...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Association of Hepato-Biliary-Pancreatic Surgery
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736739/ https://www.ncbi.nlm.nih.gov/pubmed/29264582 http://dx.doi.org/10.14701/ahbps.2017.21.4.199 |
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author | Ha, Soo-Min Hwang, Shin Song, Gi-Won Ahn, Chul-Soo Moon, Deok-Bog Ha, Tae-Yong Jung, Dong-Hwan Park, Gil-Chun Kim, Ki-Hun Kim, Dae-Yeon Namgung, Jungman Kang, Woo-Hyoung Kim, Seok-Hwan Jwa, Eunkyoung Kwon, Jae-Hyeon Cho, Hui-Dong Jung, Yong-Kyu Kang, Sang-Hyeon Lee, Sung-Gyu |
author_facet | Ha, Soo-Min Hwang, Shin Song, Gi-Won Ahn, Chul-Soo Moon, Deok-Bog Ha, Tae-Yong Jung, Dong-Hwan Park, Gil-Chun Kim, Ki-Hun Kim, Dae-Yeon Namgung, Jungman Kang, Woo-Hyoung Kim, Seok-Hwan Jwa, Eunkyoung Kwon, Jae-Hyeon Cho, Hui-Dong Jung, Yong-Kyu Kang, Sang-Hyeon Lee, Sung-Gyu |
author_sort | Ha, Soo-Min |
collection | PubMed |
description | BACKGROUNDS/AIMS: Model for End-stage Liver Disease (MELD) score was adopted in June 2016 in Korea. METHODS: We analyzed changes in volumes and outcomes of deceased donor liver transplantation (DDLT) for 1 year before and after introduction of MELD scoring at Asan Medical Center. RESULTS: There were 64 cases of DDLT in 1 year before MELD introduction and 106 in 1 year after MELD introduction, an increase of 65%. The volume of DDLTs abruptly increased during first 3 months, but then returned to its usual level before MELD introduction, which indicated 3-month depletion of accumulated recipient pool with high MELD scores. The number of pediatric DDLT cases increased from 3 before MELD introduction to 11 after it, making up 21.4% and 47.8% of all cases of pediatric liver transplantation, respectively. The number of cases of retransplanted DDLTs increased from 4 to 27, representing 6.3% and 25.5% of all DDLT cases, respectively. The number of status 1 DDLT cases increased from 5 to 12, being 7.8% and 11.3% of all cases. Patient survival outcomes were similar before and after MELD introduction. CONCLUSIONS: The number of DDLTs temporarily increased after adoption of MELD scoring due to accumulated recipient pool with high MELD scores. The numbers of retransplanted and pediatric DDLT cases significantly increased. Patient survival in adult and pediatric DDLT was comparable before and after adoption of MELD scoring. These results imply that Korean MELD score-based allocation system was successfully established within its first year. |
format | Online Article Text |
id | pubmed-5736739 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Korean Association of Hepato-Biliary-Pancreatic Surgery |
record_format | MEDLINE/PubMed |
spelling | pubmed-57367392017-12-20 Successful introduction of Model for End-stage Liver Disease scoring in deceased donor liver transplantation in Korea: analysis of first 1 year experience at a high-volume transplantation center Ha, Soo-Min Hwang, Shin Song, Gi-Won Ahn, Chul-Soo Moon, Deok-Bog Ha, Tae-Yong Jung, Dong-Hwan Park, Gil-Chun Kim, Ki-Hun Kim, Dae-Yeon Namgung, Jungman Kang, Woo-Hyoung Kim, Seok-Hwan Jwa, Eunkyoung Kwon, Jae-Hyeon Cho, Hui-Dong Jung, Yong-Kyu Kang, Sang-Hyeon Lee, Sung-Gyu Ann Hepatobiliary Pancreat Surg Original Article BACKGROUNDS/AIMS: Model for End-stage Liver Disease (MELD) score was adopted in June 2016 in Korea. METHODS: We analyzed changes in volumes and outcomes of deceased donor liver transplantation (DDLT) for 1 year before and after introduction of MELD scoring at Asan Medical Center. RESULTS: There were 64 cases of DDLT in 1 year before MELD introduction and 106 in 1 year after MELD introduction, an increase of 65%. The volume of DDLTs abruptly increased during first 3 months, but then returned to its usual level before MELD introduction, which indicated 3-month depletion of accumulated recipient pool with high MELD scores. The number of pediatric DDLT cases increased from 3 before MELD introduction to 11 after it, making up 21.4% and 47.8% of all cases of pediatric liver transplantation, respectively. The number of cases of retransplanted DDLTs increased from 4 to 27, representing 6.3% and 25.5% of all DDLT cases, respectively. The number of status 1 DDLT cases increased from 5 to 12, being 7.8% and 11.3% of all cases. Patient survival outcomes were similar before and after MELD introduction. CONCLUSIONS: The number of DDLTs temporarily increased after adoption of MELD scoring due to accumulated recipient pool with high MELD scores. The numbers of retransplanted and pediatric DDLT cases significantly increased. Patient survival in adult and pediatric DDLT was comparable before and after adoption of MELD scoring. These results imply that Korean MELD score-based allocation system was successfully established within its first year. Korean Association of Hepato-Biliary-Pancreatic Surgery 2017-11 2017-11-30 /pmc/articles/PMC5736739/ /pubmed/29264582 http://dx.doi.org/10.14701/ahbps.2017.21.4.199 Text en Copyright © 2017 by The Korean Association of Hepato-Biliary-Pancreatic Surgery http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Ha, Soo-Min Hwang, Shin Song, Gi-Won Ahn, Chul-Soo Moon, Deok-Bog Ha, Tae-Yong Jung, Dong-Hwan Park, Gil-Chun Kim, Ki-Hun Kim, Dae-Yeon Namgung, Jungman Kang, Woo-Hyoung Kim, Seok-Hwan Jwa, Eunkyoung Kwon, Jae-Hyeon Cho, Hui-Dong Jung, Yong-Kyu Kang, Sang-Hyeon Lee, Sung-Gyu Successful introduction of Model for End-stage Liver Disease scoring in deceased donor liver transplantation in Korea: analysis of first 1 year experience at a high-volume transplantation center |
title | Successful introduction of Model for End-stage Liver Disease scoring in deceased donor liver transplantation in Korea: analysis of first 1 year experience at a high-volume transplantation center |
title_full | Successful introduction of Model for End-stage Liver Disease scoring in deceased donor liver transplantation in Korea: analysis of first 1 year experience at a high-volume transplantation center |
title_fullStr | Successful introduction of Model for End-stage Liver Disease scoring in deceased donor liver transplantation in Korea: analysis of first 1 year experience at a high-volume transplantation center |
title_full_unstemmed | Successful introduction of Model for End-stage Liver Disease scoring in deceased donor liver transplantation in Korea: analysis of first 1 year experience at a high-volume transplantation center |
title_short | Successful introduction of Model for End-stage Liver Disease scoring in deceased donor liver transplantation in Korea: analysis of first 1 year experience at a high-volume transplantation center |
title_sort | successful introduction of model for end-stage liver disease scoring in deceased donor liver transplantation in korea: analysis of first 1 year experience at a high-volume transplantation center |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736739/ https://www.ncbi.nlm.nih.gov/pubmed/29264582 http://dx.doi.org/10.14701/ahbps.2017.21.4.199 |
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