Cargando…

Successful introduction of Model for End-stage Liver Disease scoring in deceased donor liver transplantation in Korea: analysis of first 1 year experience at a high-volume transplantation center

BACKGROUNDS/AIMS: Model for End-stage Liver Disease (MELD) score was adopted in June 2016 in Korea. METHODS: We analyzed changes in volumes and outcomes of deceased donor liver transplantation (DDLT) for 1 year before and after introduction of MELD scoring at Asan Medical Center. RESULTS: There were...

Descripción completa

Detalles Bibliográficos
Autores principales: Ha, Soo-Min, Hwang, Shin, Song, Gi-Won, Ahn, Chul-Soo, Moon, Deok-Bog, Ha, Tae-Yong, Jung, Dong-Hwan, Park, Gil-Chun, Kim, Ki-Hun, Kim, Dae-Yeon, Namgung, Jungman, Kang, Woo-Hyoung, Kim, Seok-Hwan, Jwa, Eunkyoung, Kwon, Jae-Hyeon, Cho, Hui-Dong, Jung, Yong-Kyu, Kang, Sang-Hyeon, Lee, Sung-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Hepato-Biliary-Pancreatic Surgery 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736739/
https://www.ncbi.nlm.nih.gov/pubmed/29264582
http://dx.doi.org/10.14701/ahbps.2017.21.4.199
_version_ 1783287419761590272
author Ha, Soo-Min
Hwang, Shin
Song, Gi-Won
Ahn, Chul-Soo
Moon, Deok-Bog
Ha, Tae-Yong
Jung, Dong-Hwan
Park, Gil-Chun
Kim, Ki-Hun
Kim, Dae-Yeon
Namgung, Jungman
Kang, Woo-Hyoung
Kim, Seok-Hwan
Jwa, Eunkyoung
Kwon, Jae-Hyeon
Cho, Hui-Dong
Jung, Yong-Kyu
Kang, Sang-Hyeon
Lee, Sung-Gyu
author_facet Ha, Soo-Min
Hwang, Shin
Song, Gi-Won
Ahn, Chul-Soo
Moon, Deok-Bog
Ha, Tae-Yong
Jung, Dong-Hwan
Park, Gil-Chun
Kim, Ki-Hun
Kim, Dae-Yeon
Namgung, Jungman
Kang, Woo-Hyoung
Kim, Seok-Hwan
Jwa, Eunkyoung
Kwon, Jae-Hyeon
Cho, Hui-Dong
Jung, Yong-Kyu
Kang, Sang-Hyeon
Lee, Sung-Gyu
author_sort Ha, Soo-Min
collection PubMed
description BACKGROUNDS/AIMS: Model for End-stage Liver Disease (MELD) score was adopted in June 2016 in Korea. METHODS: We analyzed changes in volumes and outcomes of deceased donor liver transplantation (DDLT) for 1 year before and after introduction of MELD scoring at Asan Medical Center. RESULTS: There were 64 cases of DDLT in 1 year before MELD introduction and 106 in 1 year after MELD introduction, an increase of 65%. The volume of DDLTs abruptly increased during first 3 months, but then returned to its usual level before MELD introduction, which indicated 3-month depletion of accumulated recipient pool with high MELD scores. The number of pediatric DDLT cases increased from 3 before MELD introduction to 11 after it, making up 21.4% and 47.8% of all cases of pediatric liver transplantation, respectively. The number of cases of retransplanted DDLTs increased from 4 to 27, representing 6.3% and 25.5% of all DDLT cases, respectively. The number of status 1 DDLT cases increased from 5 to 12, being 7.8% and 11.3% of all cases. Patient survival outcomes were similar before and after MELD introduction. CONCLUSIONS: The number of DDLTs temporarily increased after adoption of MELD scoring due to accumulated recipient pool with high MELD scores. The numbers of retransplanted and pediatric DDLT cases significantly increased. Patient survival in adult and pediatric DDLT was comparable before and after adoption of MELD scoring. These results imply that Korean MELD score-based allocation system was successfully established within its first year.
format Online
Article
Text
id pubmed-5736739
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Korean Association of Hepato-Biliary-Pancreatic Surgery
record_format MEDLINE/PubMed
spelling pubmed-57367392017-12-20 Successful introduction of Model for End-stage Liver Disease scoring in deceased donor liver transplantation in Korea: analysis of first 1 year experience at a high-volume transplantation center Ha, Soo-Min Hwang, Shin Song, Gi-Won Ahn, Chul-Soo Moon, Deok-Bog Ha, Tae-Yong Jung, Dong-Hwan Park, Gil-Chun Kim, Ki-Hun Kim, Dae-Yeon Namgung, Jungman Kang, Woo-Hyoung Kim, Seok-Hwan Jwa, Eunkyoung Kwon, Jae-Hyeon Cho, Hui-Dong Jung, Yong-Kyu Kang, Sang-Hyeon Lee, Sung-Gyu Ann Hepatobiliary Pancreat Surg Original Article BACKGROUNDS/AIMS: Model for End-stage Liver Disease (MELD) score was adopted in June 2016 in Korea. METHODS: We analyzed changes in volumes and outcomes of deceased donor liver transplantation (DDLT) for 1 year before and after introduction of MELD scoring at Asan Medical Center. RESULTS: There were 64 cases of DDLT in 1 year before MELD introduction and 106 in 1 year after MELD introduction, an increase of 65%. The volume of DDLTs abruptly increased during first 3 months, but then returned to its usual level before MELD introduction, which indicated 3-month depletion of accumulated recipient pool with high MELD scores. The number of pediatric DDLT cases increased from 3 before MELD introduction to 11 after it, making up 21.4% and 47.8% of all cases of pediatric liver transplantation, respectively. The number of cases of retransplanted DDLTs increased from 4 to 27, representing 6.3% and 25.5% of all DDLT cases, respectively. The number of status 1 DDLT cases increased from 5 to 12, being 7.8% and 11.3% of all cases. Patient survival outcomes were similar before and after MELD introduction. CONCLUSIONS: The number of DDLTs temporarily increased after adoption of MELD scoring due to accumulated recipient pool with high MELD scores. The numbers of retransplanted and pediatric DDLT cases significantly increased. Patient survival in adult and pediatric DDLT was comparable before and after adoption of MELD scoring. These results imply that Korean MELD score-based allocation system was successfully established within its first year. Korean Association of Hepato-Biliary-Pancreatic Surgery 2017-11 2017-11-30 /pmc/articles/PMC5736739/ /pubmed/29264582 http://dx.doi.org/10.14701/ahbps.2017.21.4.199 Text en Copyright © 2017 by The Korean Association of Hepato-Biliary-Pancreatic Surgery http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Ha, Soo-Min
Hwang, Shin
Song, Gi-Won
Ahn, Chul-Soo
Moon, Deok-Bog
Ha, Tae-Yong
Jung, Dong-Hwan
Park, Gil-Chun
Kim, Ki-Hun
Kim, Dae-Yeon
Namgung, Jungman
Kang, Woo-Hyoung
Kim, Seok-Hwan
Jwa, Eunkyoung
Kwon, Jae-Hyeon
Cho, Hui-Dong
Jung, Yong-Kyu
Kang, Sang-Hyeon
Lee, Sung-Gyu
Successful introduction of Model for End-stage Liver Disease scoring in deceased donor liver transplantation in Korea: analysis of first 1 year experience at a high-volume transplantation center
title Successful introduction of Model for End-stage Liver Disease scoring in deceased donor liver transplantation in Korea: analysis of first 1 year experience at a high-volume transplantation center
title_full Successful introduction of Model for End-stage Liver Disease scoring in deceased donor liver transplantation in Korea: analysis of first 1 year experience at a high-volume transplantation center
title_fullStr Successful introduction of Model for End-stage Liver Disease scoring in deceased donor liver transplantation in Korea: analysis of first 1 year experience at a high-volume transplantation center
title_full_unstemmed Successful introduction of Model for End-stage Liver Disease scoring in deceased donor liver transplantation in Korea: analysis of first 1 year experience at a high-volume transplantation center
title_short Successful introduction of Model for End-stage Liver Disease scoring in deceased donor liver transplantation in Korea: analysis of first 1 year experience at a high-volume transplantation center
title_sort successful introduction of model for end-stage liver disease scoring in deceased donor liver transplantation in korea: analysis of first 1 year experience at a high-volume transplantation center
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736739/
https://www.ncbi.nlm.nih.gov/pubmed/29264582
http://dx.doi.org/10.14701/ahbps.2017.21.4.199
work_keys_str_mv AT hasoomin successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT hwangshin successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT songgiwon successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT ahnchulsoo successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT moondeokbog successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT hataeyong successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT jungdonghwan successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT parkgilchun successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT kimkihun successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT kimdaeyeon successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT namgungjungman successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT kangwoohyoung successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT kimseokhwan successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT jwaeunkyoung successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT kwonjaehyeon successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT chohuidong successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT jungyongkyu successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT kangsanghyeon successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter
AT leesunggyu successfulintroductionofmodelforendstageliverdiseasescoringindeceaseddonorlivertransplantationinkoreaanalysisoffirst1yearexperienceatahighvolumetransplantationcenter