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Primary gigantic leiomyosarcoma of the liver treated with portal vein embolization and liver resection

Primary hepatic leiomyosarcoma (PHL) is an extremely rare tumor. The tumor has no specific presentations and often diagnosis is delayed until it reaches a significant size. We report the case of a 69-year-old female presented with a huge PHL. Due to size of the tumor and to be operable, the patient...

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Autores principales: Giakoustidis, Dimitrios, Giakoustidis, Alexander, Goulopoulos, Thomas, Arabatzi, Ntina, Kainantidis, Aristidis, Zaraboukas, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Hepato-Biliary-Pancreatic Surgery 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736744/
https://www.ncbi.nlm.nih.gov/pubmed/29264587
http://dx.doi.org/10.14701/ahbps.2017.21.4.228
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author Giakoustidis, Dimitrios
Giakoustidis, Alexander
Goulopoulos, Thomas
Arabatzi, Ntina
Kainantidis, Aristidis
Zaraboukas, Thomas
author_facet Giakoustidis, Dimitrios
Giakoustidis, Alexander
Goulopoulos, Thomas
Arabatzi, Ntina
Kainantidis, Aristidis
Zaraboukas, Thomas
author_sort Giakoustidis, Dimitrios
collection PubMed
description Primary hepatic leiomyosarcoma (PHL) is an extremely rare tumor. The tumor has no specific presentations and often diagnosis is delayed until it reaches a significant size. We report the case of a 69-year-old female presented with a huge PHL. Due to size of the tumor and to be operable, the patient subjected to right portal vein embolization (PVE) and selective embolization of segment V. Four weeks after the PVE, liver resection was conducted (Segments V+VI bisegmentectomy plus resection of IVA). The patient had an uncomplicated post-operative course, and discharged at the 8th post-operative day. Diagnosis of PHL was confirmed by histopathological and immunohistochemical examinations. The patient refused to receive adjuvant chemotherapy, and revealed evidence of recurrence six months after the operation, and finally died 12 months after the operation and 16 months after initial diagnosis. PHL is an extremely rare tumor and often in first presentation has significant size. Radical surgery with adjuvant chemotherapy is key feature for prolonged survival.
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spelling pubmed-57367442017-12-20 Primary gigantic leiomyosarcoma of the liver treated with portal vein embolization and liver resection Giakoustidis, Dimitrios Giakoustidis, Alexander Goulopoulos, Thomas Arabatzi, Ntina Kainantidis, Aristidis Zaraboukas, Thomas Ann Hepatobiliary Pancreat Surg Case Report Primary hepatic leiomyosarcoma (PHL) is an extremely rare tumor. The tumor has no specific presentations and often diagnosis is delayed until it reaches a significant size. We report the case of a 69-year-old female presented with a huge PHL. Due to size of the tumor and to be operable, the patient subjected to right portal vein embolization (PVE) and selective embolization of segment V. Four weeks after the PVE, liver resection was conducted (Segments V+VI bisegmentectomy plus resection of IVA). The patient had an uncomplicated post-operative course, and discharged at the 8th post-operative day. Diagnosis of PHL was confirmed by histopathological and immunohistochemical examinations. The patient refused to receive adjuvant chemotherapy, and revealed evidence of recurrence six months after the operation, and finally died 12 months after the operation and 16 months after initial diagnosis. PHL is an extremely rare tumor and often in first presentation has significant size. Radical surgery with adjuvant chemotherapy is key feature for prolonged survival. Korean Association of Hepato-Biliary-Pancreatic Surgery 2017-11 2017-11-30 /pmc/articles/PMC5736744/ /pubmed/29264587 http://dx.doi.org/10.14701/ahbps.2017.21.4.228 Text en Copyright © 2017 by The Korean Association of Hepato-Biliary-Pancreatic Surgery http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Giakoustidis, Dimitrios
Giakoustidis, Alexander
Goulopoulos, Thomas
Arabatzi, Ntina
Kainantidis, Aristidis
Zaraboukas, Thomas
Primary gigantic leiomyosarcoma of the liver treated with portal vein embolization and liver resection
title Primary gigantic leiomyosarcoma of the liver treated with portal vein embolization and liver resection
title_full Primary gigantic leiomyosarcoma of the liver treated with portal vein embolization and liver resection
title_fullStr Primary gigantic leiomyosarcoma of the liver treated with portal vein embolization and liver resection
title_full_unstemmed Primary gigantic leiomyosarcoma of the liver treated with portal vein embolization and liver resection
title_short Primary gigantic leiomyosarcoma of the liver treated with portal vein embolization and liver resection
title_sort primary gigantic leiomyosarcoma of the liver treated with portal vein embolization and liver resection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736744/
https://www.ncbi.nlm.nih.gov/pubmed/29264587
http://dx.doi.org/10.14701/ahbps.2017.21.4.228
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