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Morphometric Characterization of Rat and Human Alveolar Macrophage Cell Models and their Response to Amiodarone using High Content Image Analysis
PURPOSE: Progress to the clinic may be delayed or prevented when vacuolated or “foamy” alveolar macrophages are observed during non-clinical inhalation toxicology assessment. The first step in developing methods to study this response in vitro is to characterize macrophage cell lines and their respo...
Autores principales: | Hoffman, Ewelina, Patel, Aateka, Ball, Doug, Klapwijk, Jan, Millar, Val, Kumar, Abhinav, Martin, Abigail, Mahendran, Rhamiya, Dailey, Lea Ann, Forbes, Ben, Hutter, Victoria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736774/ https://www.ncbi.nlm.nih.gov/pubmed/28540501 http://dx.doi.org/10.1007/s11095-017-2176-5 |
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