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Impact of the Immunogen Nature on the Immune Response against the Major HBV Antigens in an HBsAg and HLA-humanized Transgenic Mouse Model

Hepatitis B chronic carriage remains as a major public health problem. Protein and DNA vaccines are now widely used in therapeutic vaccine candidates. Although, the hepatitis B surface antigen (HBsAg) based vaccines have been largely studied, candidates comprising both HBsAg and core (HBcAg) either...

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Detalles Bibliográficos
Autores principales: Mancini-Bourgine, M, Guillen, G, Michel, ML, Aguilar, JC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736954/
https://www.ncbi.nlm.nih.gov/pubmed/29264317
http://dx.doi.org/10.5005/jp-journals-10018-1094