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HDAC2 and HDAC5 Up-Regulations Modulate Survivin and miR-125a-5p Expressions and Promote Hormone Therapy Resistance in Estrogen Receptor Positive Breast Cancer Cells
Intrinsic or acquired resistance to hormone therapy is frequently reported in estrogen receptor positive (ER(+)) breast cancer patients. Even though dysregulations of histone deacetylases (HDACs) are known to promote cancer cells survival, the role of different HDACs in the induction of hormone ther...
Autores principales: | Huang, Wen-Tsung, Tsai, Yu-Hsuan, Chen, Shang-Hung, Kuo, Ching-Wen, Kuo, Yao-Lung, Lee, Kuo-Ting, Chen, Wen-Chung, Wu, Pei Chih, Chuang, Chun-Yu, Cheng, Siao Muk, Lin, Chun-Hui, Leung, Euphemia Yee, Chang, Yung-Chieh, Cheung, Chun Hei Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736991/ https://www.ncbi.nlm.nih.gov/pubmed/29326587 http://dx.doi.org/10.3389/fphar.2017.00902 |
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