A c-Src Inhibitor Peptide Based on Connexin43 Exerts Neuroprotective Effects through the Inhibition of Glial Hemichannel Activity

The non-receptor tyrosine kinase c-Src is an important mediator in several signaling pathways related to neuroinflammation. Our previous study showed that cortical injection of kainic acid (KA) promoted a transient increase in c-Src activity in reactive astrocytes surrounding the neuronal lesion. As...

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Detalles Bibliográficos
Autores principales: Gangoso, Ester, Talaverón, Rocío, Jaraíz-Rodríguez, Myriam, Domínguez-Prieto, Marta, Ezan, Pascal, Koulakoff, Annette, Medina, José M., Giaume, Christian, Tabernero, Arantxa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737028/
https://www.ncbi.nlm.nih.gov/pubmed/29326548
http://dx.doi.org/10.3389/fnmol.2017.00418

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