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Alterations in Mitochondrial Oxidative Stress and Mitophagy in Subjects with Prediabetes and Type 2 Diabetes Mellitus

BACKGROUND AND AIM: Hyperglycemia-mediated oxidative stress impedes cell-reparative process like autophagy, which has been implicated in impairment of β-cell function in type 2 diabetes mellitus (T2DM). However, the role of mitophagy (selective mitochondrial autophagy) in progression of hyperglycemi...

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Detalles Bibliográficos
Autores principales:	Bhansali, Shipra, Bhansali, Anil, Walia, Rama, Saikia, Uma Nahar, Dhawan, Veena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737033/ https://www.ncbi.nlm.nih.gov/pubmed/29326655 http://dx.doi.org/10.3389/fendo.2017.00347

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