Short inverted repeats contribute to localized mutability in human somatic cells

Selected repetitive sequences termed short inverted repeats (SIRs) have the propensity to form secondary DNA structures called hairpins. SIRs comprise palindromic arm sequences separated by short spacer sequences that form the hairpin stem and loop respectively. Here, we show that SIRs confer an inc...

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Detalles Bibliográficos
Autores principales: Zou, Xueqing, Morganella, Sandro, Glodzik, Dominik, Davies, Helen, Li, Yilin, Stratton, Michael R., Nik-Zainal, Serena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737083/
https://www.ncbi.nlm.nih.gov/pubmed/28977645
http://dx.doi.org/10.1093/nar/gkx731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737083/
https://www.ncbi.nlm.nih.gov/pubmed/28977645
http://dx.doi.org/10.1093/nar/gkx731

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