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Visualization of conformational variability in the domains of long single-stranded RNA molecules

We demonstrate an application of atomic force microscopy (AFM) for the structural analysis of long single-stranded RNA (>1 kb), focusing on 28S ribosomal RNA (rRNA). Generally, optimization of the conditions required to obtain three-dimensional (3D) structures of long RNA molecules is a challengi...

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Detalles Bibliográficos
Autores principales:	Gilmore, Jamie L., Yoshida, Aiko, Hejna, James A., Takeyasu, Kunio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737216/ https://www.ncbi.nlm.nih.gov/pubmed/28591846 http://dx.doi.org/10.1093/nar/gkx502

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