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Enrichment of dynamic chromosomal crosslinks drive phase separation of the nucleolus

Regions of highly repetitive DNA, such as those found in the nucleolus, show a self-organization that is marked by spatial segregation and frequent self-interaction. The mechanisms that underlie the sequestration of these sub-domains are largely unknown. Using a stochastic, bead-spring representatio...

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Detalles Bibliográficos
Autores principales:	Hult, Caitlin, Adalsteinsson, David, Vasquez, Paula A., Lawrimore, Josh, Bennett, Maggie, York, Alyssa, Cook, Diana, Yeh, Elaine, Forest, Mark Gregory, Bloom, Kerry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737219/ https://www.ncbi.nlm.nih.gov/pubmed/28977453 http://dx.doi.org/10.1093/nar/gkx741

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