H2B ubiquitylation and the histone chaperone Asf1 cooperatively mediate the formation and maintenance of heterochromatin silencing

Heterochromatin is a heritable form of gene repression, with critical roles in development and cell identity. Understanding how chromatin factors results in such repression is a fundamental question. Chromatin is assembled and disassembled during transcription, replication and repair by anti-silenci...

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Detalles Bibliográficos
Autores principales: Wu, Meng-Ying, Lin, Chia-Yeh, Tseng, Hsin-Yi, Hsu, Fei-Man, Chen, Pao-Yang, Kao, Cheng-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737242/
https://www.ncbi.nlm.nih.gov/pubmed/28520954
http://dx.doi.org/10.1093/nar/gkx422

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