Comparative analysis of chimeric ZFP-, TALE- and Cas9-piggyBac transposases for integration into a single locus in human cells

Integrating DNA delivery systems hold promise for many applications including treatment of diseases; however, targeted integration is needed for improved safety. The piggyBac (PB) transposon system is a highly active non-viral gene delivery system capable of integrating defined DNA segments into hos...

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Detalles Bibliográficos
Autores principales: Luo, Wentian, Galvan, Daniel L., Woodard, Lauren E., Dorset, Dan, Levy, Shawn, Wilson, Matthew H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737283/
https://www.ncbi.nlm.nih.gov/pubmed/28666380
http://dx.doi.org/10.1093/nar/gkx572

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