Integrated analysis of individual codon contribution to protein biosynthesis reveals a new approach to improving the basis of rational gene design

Gene codon optimization may be impaired by the misinterpretation of frequency and optimality of codons. Although recent studies have revealed the effects of codon usage bias (CUB) on protein biosynthesis, an integrated perspective of the biological role of individual codons remains unknown. Unlike o...

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Detalles Bibliográficos
Autores principales: Villada, Juan C., Brustolini, Otávio José Bernardes, Batista da Silveira, Wendel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737324/
https://www.ncbi.nlm.nih.gov/pubmed/28449100
http://dx.doi.org/10.1093/dnares/dsx014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737324/
https://www.ncbi.nlm.nih.gov/pubmed/28449100
http://dx.doi.org/10.1093/dnares/dsx014

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