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Integrated analysis of individual codon contribution to protein biosynthesis reveals a new approach to improving the basis of rational gene design
Gene codon optimization may be impaired by the misinterpretation of frequency and optimality of codons. Although recent studies have revealed the effects of codon usage bias (CUB) on protein biosynthesis, an integrated perspective of the biological role of individual codons remains unknown. Unlike o...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737324/ https://www.ncbi.nlm.nih.gov/pubmed/28449100 http://dx.doi.org/10.1093/dnares/dsx014 |