Multiplexed analysis of fixed tissue RNA using Ligation in situ Hybridization

Clinical tissues are prepared for histological analysis and long-term storage via formalin fixation and paraffin embedding (FFPE). The FFPE process results in fragmentation and chemical modification of RNA, rendering it less suitable for analysis by techniques that rely on reverse transcription (RT)...

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Detalles Bibliográficos
Autores principales: Credle, Joel J., Itoh, Christopher Y., Yuan, Tiezheng, Sharma, Rajni, Scott, Erick R., Workman, Rachael E., Fan, Yunfan, Housseau, Franck, Llosa, Nicolas J., Bell, W. Robert., Miller, Heather, Zhang, Sean X., Timp, Winston, Larman, H. Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737328/
https://www.ncbi.nlm.nih.gov/pubmed/28854731
http://dx.doi.org/10.1093/nar/gkx471

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