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Structural insights into species-specific features of the ribosome from the human pathogen Mycobacterium tuberculosis

Ribosomes from Mycobacterium tuberculosis (Mtb) possess species-specific ribosomal RNA (rRNA) expansion segments and ribosomal proteins (rProtein). Here, we present the near-atomic structures of the Mtb 50S ribosomal subunit and the complete Mtb 70S ribosome, solved by cryo-electron microscopy. Upon...

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Detalles Bibliográficos
Autores principales:	Yang, Kailu, Chang, Jeng-Yih, Cui, Zhicheng, Li, Xiaojun, Meng, Ran, Duan, Lijun, Thongchol, Jirapat, Jakana, Joanita, Huwe, Christoph M., Sacchettini, James C., Zhang, Junjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737476/ https://www.ncbi.nlm.nih.gov/pubmed/28977617 http://dx.doi.org/10.1093/nar/gkx785

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