Homeostatic nuclear RAGE–ATM interaction is essential for efficient DNA repair

The integrity of genome is a prerequisite for healthy life. Indeed, defects in DNA repair have been associated with several human diseases, including tissue-fibrosis, neurodegeneration and cancer. Despite decades of extensive research, the spatio-mechanical processes of double-strand break (DSB)-rep...

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Detalles Bibliográficos
Autores principales: Kumar, Varun, Fleming, Thomas, Terjung, Stefan, Gorzelanny, Christian, Gebhardt, Christoffer, Agrawal, Raman, Mall, Marcus A., Ranzinger, Julia, Zeier, Martin, Madhusudhan, Thati, Ranjan, Satish, Isermann, Berend, Liesz, Arthur, Deshpande, Divija, Häring, Hans-Ulrich, Biswas, Subrata K, Reynolds, Paul R., Hammes, Hans-Peter, Peperkok, Rainer, Angel, Peter, Herzig, Stephan, Nawroth, Peter P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737477/
https://www.ncbi.nlm.nih.gov/pubmed/28977635
http://dx.doi.org/10.1093/nar/gkx705

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