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The role of poly ADP-ribosylation in the first wave of DNA damage response

Poly ADP-ribose polymerases (PARPs) catalyze massive protein poly ADP-ribosylation (PARylation) within seconds after the induction of DNA single- or double-strand breaks. PARylation occurs at or near the sites of DNA damage and promotes the recruitment of DNA repair factors via their poly ADP-ribose...

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Detalles Bibliográficos
Autores principales:	Liu, Chao, Vyas, Aditi, Kassab, Muzaffer A., Singh, Anup K., Yu, Xiaochun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Survey and Summary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737498/ https://www.ncbi.nlm.nih.gov/pubmed/28854736 http://dx.doi.org/10.1093/nar/gkx565

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