Genome-scale detection of positive selection in nine primates predicts human-virus evolutionary conflicts

Hotspots of rapid genome evolution hold clues about human adaptation. We present a comparative analysis of nine whole-genome sequenced primates to identify high-confidence targets of positive selection. We find strong statistical evidence for positive selection in 331 protein-coding genes (3%), pinp...

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Detalles Bibliográficos
Autores principales: van der Lee, Robin, Wiel, Laurens, van Dam, Teunis J.P., Huynen, Martijn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737536/
https://www.ncbi.nlm.nih.gov/pubmed/28977405
http://dx.doi.org/10.1093/nar/gkx704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737536/
https://www.ncbi.nlm.nih.gov/pubmed/28977405
http://dx.doi.org/10.1093/nar/gkx704

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