Cargando…

Leonurine Exerts Antidepressant-Like Effects in the Chronic Mild Stress-Induced Depression Model in Mice by Inhibiting Neuroinflammation

BACKGROUND: Leonurine is an active alkaloid that is extracted from Traditional Chinese Medicine Herba leonuri. Emerging evidence indicates that leonurine produces neuroprotective effects in ischemic stroke, Parkinson’s disease, and Alzheimer’s disease. However, the effect of leonurine in neuropsychi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jia, Miaomiao, Li, Chenxin, Zheng, Ying, Ding, Xiaojing, Chen, Meng, Ding, Jianhua, Du, Renhong, Lu, Ming, Hu, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Regular Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737563/ https://www.ncbi.nlm.nih.gov/pubmed/29016795 http://dx.doi.org/10.1093/ijnp/pyx062

Ejemplares similares

Leonurine suppresses neuroinflammation through promoting oligodendrocyte maturation
por: Jin, Min, et al.
Publicado: (2018)

Cucurbitacin B Exerts Significant Antidepressant-Like Effects in a Chronic Unpredictable Mild Stress Model of Depression: Involvement of the Hippocampal BDNF-TrkB System
por: Ge, Jian-Bin, et al.
Publicado: (2023)

Andrographolide Exerts Significant Antidepressant-Like Effects Involving the Hippocampal BDNF System in Mice
por: Zhang, Jing-Jing, et al.
Publicado: (2019)

Antidepressant Effects of Rhodomyrtone in Mice with Chronic Unpredictable Mild Stress-Induced Depression
por: Chai, Huihui, et al.
Publicado: (2018)

The Guanidine Pseudoalkaloids 10-Methoxy-Leonurine and Leonurine Act as Competitive Inhibitors of Tyrosinase
por: Kim, Jang Hoon, et al.
Publicado: (2020)

Leonurine Attenuates Hyperalgesia in Mice with Induced Adenomyosis
por: Nie, Jichan, et al.
Publicado: (2017)

Matrine Exerts Antidepressant-Like Effects on Mice: Role of the Hippocampal PI3K/Akt/mTOR Signaling
por: Wu, Zhonghua, et al.
Publicado: (2018)

Alkaloid leonurine exerts anti‐inflammatory effects via modulating MST1 expression in trophoblast cells
por: Zong, Fang, et al.
Publicado: (2021)

Muscone with Attenuation of Neuroinflammation and Oxidative Stress Exerts Antidepressant-Like Effect in Mouse Model of Chronic Restraint Stress
por: Liu, Hua, et al.
Publicado: (2022)

Xiaoyaosan Exerts Antidepressant Effect by Downregulating RAGE Expression in Cingulate Gyrus of Depressive-Like Mice
por: Yan, Weixin, et al.
Publicado: (2021)

BTRX-246040 Acts Through the Ventrolateral Periaqueductal Gray to Exert Antidepressant-Relevant Actions in Mice
por: Li, Zhenlong, et al.
Publicado: (2023)

Antidepressant-Like Activity of Myelophil via Attenuation of Microglial-Mediated Neuroinflammation in Mice Undergoing Unpredictable Chronic Mild Stress
por: Lee, Jin-Seok, et al.
Publicado: (2019)

Limonene through Attenuation of Neuroinflammation and Nitrite Level Exerts Antidepressant-Like Effect on Mouse Model of Maternal Separation Stress
por: Lorigooini, Zahra, et al.
Publicado: (2021)

Corrigendum: Xiaoyaosan exerts antidepressant effect by downregulating RAGE expression in cingulate gyrus of depressive-like mice
por: Yan, Weixin, et al.
Publicado: (2022)

Xiaoyaosan exerts antidepressant-like effects by regulating the functions of astrocytes and EAATs in the prefrontal cortex of mice
por: Liu, Yan, et al.
Publicado: (2019)

Leonurine, a potential drug for the treatment of cardiovascular system and central nervous system diseases
por: Huang, Lu, et al.
Publicado: (2020)

Leonurine Attenuates Obesity-Related Vascular Dysfunction and Inflammation
por: Shi, Xiao-Dong, et al.
Publicado: (2022)

Leonurine: A compound with the potential to prevent acute lung injury
por: Zhang, Guoying, et al.
Publicado: (2022)

G721-0282 Exerts Anxiolytic-Like Effects on Chronic Unpredictable Mild Stress in Mice Through Inhibition of Chitinase-3-Like 1-Mediated Neuroinflammation
por: Ham, Hyeon Joo, et al.
Publicado: (2022)

Antidepressant-Like Effects of Cordycepin in a Mice Model of Chronic Unpredictable Mild Stress
por: Tianzhu, Zhang, et al.
Publicado: (2014)

Stability of frontal alpha asymmetry in depressed patients during antidepressant treatment
por: van der Vinne, Nikita, et al.
Publicado: (2019)

Natural products in drug discovery and development: Synthesis and medicinal perspective of leonurine
por: Li, Zhaoyi, et al.
Publicado: (2022)

A literature review: mechanisms of antitumor pharmacological action of leonurine alkaloid
por: Cao, Qiang, et al.
Publicado: (2023)

Sex Differences in Responses to Antidepressant Augmentations in Treatment-Resistant Depression
por: Moderie, Christophe, et al.
Publicado: (2022)

The Hepatoprotective Effect of Leonurine Hydrochloride Against Alcoholic Liver Disease Based on Transcriptomic and Metabolomic Analysis
por: Wu, Ke-Jia, et al.
Publicado: (2022)

Choroid plexus enlargement is associated with neuroinflammation and reduction of blood brain barrier permeability in depression
por: Althubaity, Noha, et al.
Publicado: (2021)

Antidepressant-like Effects of Polygonum minus Aqueous Extract in Chronic Ultra-Mild Stress-Induced Depressive Mice Model
por: Bashir, Muhammad Irfan, et al.
Publicado: (2022)

Low-dose S-ketamine exerts antidepressant-like effects via enhanced hippocampal synaptic plasticity in postpartum depression rats
por: Ren, Zhuoyu, et al.
Publicado: (2021)

Progranulin from different gliocytes in the nucleus accumbens exerts distinct roles in FTD- and neuroinflammation-induced depression-like behaviors
por: Wang, Jing, et al.
Publicado: (2022)

Z-Guggulsterone Produces Antidepressant-Like Effects in Mice through Activation of the BDNF Signaling Pathway
por: Liu, Feng-Guo, et al.
Publicado: (2017)

Novel Therapeutic Effects of Leonurine On Ischemic Stroke: New Mechanisms of BBB Integrity
por: Zhang, Qiu-Yan, et al.
Publicado: (2017)

Rice Germ Ameliorated Chronic Unpredictable Mild Stress-Induced Depressive-like Behavior by Reducing Neuroinflammation
por: Batsukh, Sosorburam, et al.
Publicado: (2022)

Apocynum venetum Leaf Extract Exerts Antidepressant-Like Effects and Inhibits Hippocampal and Cortical Apoptosis of Rats Exposed to Chronic Unpredictable Mild Stress
por: Wu, Ting, et al.
Publicado: (2018)

Echinacoside exerts antidepressant-like effects through enhancing BDNF-CREB pathway and inhibiting neuroinflammation via regulating microglia M1/M2 polarization and JAK1/STAT3 pathway
por: Lu, Renrui, et al.
Publicado: (2023)

An investigation of cortical thickness and antidepressant response in major depressive disorder: A CAN-BIND study report
por: Suh, Jee Su, et al.
Publicado: (2020)

Accelerated brain aging in major depressive disorder and antidepressant treatment response: A CAN-BIND report
por: Ballester, Pedro L., et al.
Publicado: (2021)

Inhibitory Neurons in Nucleus Tractus Solitarius Are Involved in Decrease of Heart Rate Variability and Development of Depression-Like Behaviors in Temporal Lobe Epilepsy
por: Aimaier, Guliqiemu, et al.
Publicado: (2023)

Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis
por: Meng, Pan, et al.
Publicado: (2023)

Leonurine ameliorates D-galactose-induced aging in mice through activation of the Nrf2 signalling pathway
por: Chen, Peng, et al.
Publicado: (2019)

Transcranial Magnetic Stimulation Markers of Antidepressant Treatment in Adolescents With Major Depressive Disorder
por: Doruk Camsari, Deniz, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_jlg02gugfjpclmkjfn0bqoknmm