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A G-quadruplex motif in an envelope gene promoter regulates transcription and virion secretion in HBV genotype B

HBV genotypes differ in pathogenicity. In addition, genotype-specific differences in the regulation of transcription and virus replication exist in HBV, but the underlying mechanisms are unknown. Here, we show the presence of a G-quadruplex motif in the promoter of the preS2/S gene; this G-quadruple...

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Detalles Bibliográficos
Autores principales: Biswas, Banhi, Kandpal, Manish, Vivekanandan, Perumal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737607/
https://www.ncbi.nlm.nih.gov/pubmed/28981800
http://dx.doi.org/10.1093/nar/gkx823