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Determination of tRNA aminoacylation levels by high-throughput sequencing

Transfer RNA (tRNA) decodes mRNA codons when aminoacylated (charged) with an amino acid at its 3′ end. Charged tRNAs turn over rapidly in cells, and variations in charged tRNA fractions are known to be a useful parameter in cellular responses to stress. tRNA charging fractions can be measured for in...

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Detalles Bibliográficos
Autores principales:	Evans, Molly E., Clark, Wesley C., Zheng, Guanqun, Pan, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737633/ https://www.ncbi.nlm.nih.gov/pubmed/28586482 http://dx.doi.org/10.1093/nar/gkx514

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