Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture

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Changes in mature microRNA (miRNA) levels that occur downstream of signaling cascades play an important role during human development and disease. However, the regulation of primary microRNA (pri-miRNA) genes remains to be dissected in detail. To address this, we followed a data-driven approach and...

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Detalles Bibliográficos
Autores principales: Bouvy-Liivrand, Maria, Hernández de Sande, Ana, Pölönen, Petri, Mehtonen, Juha, Vuorenmaa, Tapio, Niskanen, Henri, Sinkkonen, Lasse, Kaikkonen, Minna Unelma, Heinäniemi, Merja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737680/
https://www.ncbi.nlm.nih.gov/pubmed/28973462
http://dx.doi.org/10.1093/nar/gkx680
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