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Cmr1 enables efficient RNA and DNA interference of a III-B CRISPR–Cas system by binding to target RNA and crRNA
CRISPR–Cas (clustered regularly interspaced short palindromic repeats-CRISPR-associated) systems provide adaptive immunity against invasive nucleic acids guided by CRISPR RNAs (crRNAs) in archaea and bacteria. Type III CRISPR–Cas effector complexes show RNA cleavage and RNA-activated DNA cleavage ac...
Autores principales: | Li, Yingjun, Zhang, Yan, Lin, Jinzhong, Pan, Saifu, Han, Wenyuan, Peng, Nan, Liang, Yun Xiang, She, Qunxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737701/ https://www.ncbi.nlm.nih.gov/pubmed/28977458 http://dx.doi.org/10.1093/nar/gkx791 |
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