An in vivo genetic screen for genes involved in spliced leader trans-splicing indicates a crucial role for continuous de novo spliced leader RNP assembly

Spliced leader (SL) trans-splicing is a critical element of gene expression in a number of eukaryotic groups. This process is arguably best understood in nematodes, where biochemical and molecular studies in Caenorhabditis elegans and Ascaris suum have identified key steps and factors involved. Desp...

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Detalles Bibliográficos
Autores principales: Philippe, Lucas, Pandarakalam, George C., Fasimoye, Rotimi, Harrison, Neale, Connolly, Bernadette, Pettitt, Jonathan, Müller, Berndt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737717/
https://www.ncbi.nlm.nih.gov/pubmed/28582530
http://dx.doi.org/10.1093/nar/gkx500

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