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Unbiased Identification of T-Cell Receptors Targeting Immunodominant Peptide–MHC Complexes for T-Cell Receptor Immunotherapy

T-cell receptor (TCR) immunotherapy uses T cells engineered with new TCRs to enable detection and killing of cancer cells. Efficacy of TCR immunotherapy depends on targeting antigenic peptides that are efficiently presented by the best-suited major histocompatibility complex (MHC) molecules of cance...

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Detalles Bibliográficos
Autores principales:	Lorenz, Felix K.M., Ellinger, Christian, Kieback, Elisa, Wilde, Susanne, Lietz, Maria, Schendel, Dolores J., Uckert, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc. 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737719/ https://www.ncbi.nlm.nih.gov/pubmed/28950731 http://dx.doi.org/10.1089/hum.2017.122

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