The interaction between cytosine methylation and processes of DNA replication and repair shape the mutational landscape of cancer genomes

Methylated cytosines (5mCs) are frequently mutated in the genome. However, no studies have yet comprehensively analysed mutation–methylation associations across cancer types. Here we analyse 916 cancer genomes, together with tissue type-specific methylation and replication timing data. We describe a...

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Detalles Bibliográficos
Autores principales: Poulos, Rebecca C., Olivier, Jake, Wong, Jason W.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737810/
https://www.ncbi.nlm.nih.gov/pubmed/28531315
http://dx.doi.org/10.1093/nar/gkx463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737810/
https://www.ncbi.nlm.nih.gov/pubmed/28531315
http://dx.doi.org/10.1093/nar/gkx463

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