Naturally existing isoforms of miR-222 have distinct functions

Deep-sequencing reveals extensive variation in the sequence of endogenously expressed microRNAs (termed ‘isomiRs’) in human cell lines and tissues, especially in relation to the 3′ end. From the immunoprecipitation of the microRNA-binding protein Argonaute and the sequencing of associated small RNAs...

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Detalles Bibliográficos
Autores principales: Yu, Feng, Pillman, Katherine A., Neilsen, Corine T., Toubia, John, Lawrence, David M., Tsykin, Anna, Gantier, Michael P., Callen, David F., Goodall, Gregory J., Bracken, Cameron P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737821/
https://www.ncbi.nlm.nih.gov/pubmed/28981911
http://dx.doi.org/10.1093/nar/gkx788

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