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Allosteric regulation of Csx1, a type IIIB-associated CARF domain ribonuclease by RNAs carrying a tetraadenylate tail

CRISPR–Cas systems protect prokaryotes against invading viruses and plasmids. The system is associated with a large number of Cas accessory proteins among which many contain a CARF (CRISPR-associated Rossmann fold) domain implicated in ligand binding and a HEPN (higher eukaryotes and prokaryotes nuc...

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Detalles Bibliográficos
Autores principales:	Han, Wenyuan, Pan, Saifu, López-Méndez, Blanca, Montoya, Guillermo, She, Qunxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737841/ https://www.ncbi.nlm.nih.gov/pubmed/28977519 http://dx.doi.org/10.1093/nar/gkx726

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