Genetic analysis of Japanese primary open-angle glaucoma patients and clinical characterization of risk alleles near CDKN2B-AS1, SIX6 and GAS7

PURPOSE: To test the genetic association between Japanese patients with primary open-angle glaucoma (POAG) and the previously reported POAG susceptibility loci and to perform genotype–phenotype analysis. METHODS: Genetic associations for 27 SNPs from 16 loci previously linked to POAG were assessed u...

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Detalles Bibliográficos
Autores principales: Shiga, Yukihiro, Nishiguchi, Koji M., Kawai, Yosuke, Kojima, Kaname, Sato, Kota, Fujita, Kosuke, Takahashi, Mai, Omodaka, Kazuko, Araie, Makoto, Kashiwagi, Kenji, Aihara, Makoto, Iwata, Takeshi, Mabuchi, Fumihiko, Takamoto, Mitsuko, Ozaki, Mineo, Kawase, Kazuhide, Fuse, Nobuo, Yamamoto, Masayuki, Yasuda, Jun, Nagasaki, Masao, Nakazawa, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737967/
https://www.ncbi.nlm.nih.gov/pubmed/29261660
http://dx.doi.org/10.1371/journal.pone.0186678

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