Detection of PrP(BSE) and prion infectivity in the ileal Peyer’s patch of young calves as early as 2 months after oral challenge with classical bovine spongiform encephalopathy

In classical bovine spongiform encephalopathy (C-BSE), an orally acquired prion disease of cattle, the ileal Peyer’s patch (IPP) represents the main entry port for the BSE agent. In earlier C-BSE pathogenesis studies, cattle at 4–6 months of age were orally challenged, while there are strong indicat...

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Detalles Bibliográficos
Autores principales: Ackermann, Ivett, Balkema-Buschmann, Anne, Ulrich, Reiner, Tauscher, Kerstin, Shawulu, James C., Keller, Markus, Fatola, Olanrewaju I., Brown, Paul, Groschup, Martin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738053/
https://www.ncbi.nlm.nih.gov/pubmed/29258602
http://dx.doi.org/10.1186/s13567-017-0495-5

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