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Self-extracellular RNA acts in synergy with exogenous danger signals to promote inflammation
Self-extracellular RNA (eRNA), released from stressed or injured cells upon various pathological situations such as ischemia-reperfusion-injury, has been shown to act as an alarmin by inducing procoagulatory and proinflammatory responses. In particular, M1-polarization of macrophages by eRNA resulte...
Autores principales: | Noll, Frederik, Behnke, Jonas, Leiting, Silke, Troidl, Kerstin, Alves, Gustavo Teixeira, Müller-Redetzky, Holger, Preissner, Klaus T., Fischer, Silvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738100/ https://www.ncbi.nlm.nih.gov/pubmed/29261777 http://dx.doi.org/10.1371/journal.pone.0190002 |
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