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Self-extracellular RNA acts in synergy with exogenous danger signals to promote inflammation

Self-extracellular RNA (eRNA), released from stressed or injured cells upon various pathological situations such as ischemia-reperfusion-injury, has been shown to act as an alarmin by inducing procoagulatory and proinflammatory responses. In particular, M1-polarization of macrophages by eRNA resulte...

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Detalles Bibliográficos
Autores principales: Noll, Frederik, Behnke, Jonas, Leiting, Silke, Troidl, Kerstin, Alves, Gustavo Teixeira, Müller-Redetzky, Holger, Preissner, Klaus T., Fischer, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738100/
https://www.ncbi.nlm.nih.gov/pubmed/29261777
http://dx.doi.org/10.1371/journal.pone.0190002

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