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Cleavage of osmosensitive transcriptional factor NFAT5 by Coxsackieviral protease 2A promotes viral replication

Nuclear factor of activated T cells 5 (NFAT5)/Tonicity enhancer binding protein (TonEBP) is a transcription factor induced by hypertonic stress in the kidney. However, the function of NFAT5 in other organs has rarely been studied, even though it is ubiquitously expressed. Indeed, although NFAT5 was...

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Detalles Bibliográficos
Autores principales: Qiu, Ye, Ye, Xin, Zhang, Huifang Mary, Hanson, Paul, Zhao, Guangze, Tong, Lei, Xie, Ronald, Yang, Decheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738146/
https://www.ncbi.nlm.nih.gov/pubmed/29220410
http://dx.doi.org/10.1371/journal.ppat.1006744