Lymphocyte opioid receptors as innovative biomarkers of osteoarthritic pain, for the assessment and risk management of opioid tailored therapy, before hip surgery, to prevent chronic pain and opioid tolerance/addiction development: OpMarkArt (Opioids-Markers-Arthroprosthesis) study protocol for a randomized controlled trial

BACKGROUND: The incidence of post-surgical chronic pain ranges between 20% and 40% in Europe. Osteoarthritis pain after prosthesis implantation is one of the most severe secondary syndromes, depending not only on surgery but also on organic changes before and after joints replacement. No data are av...

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Detalles Bibliográficos
Autores principales: Malafoglia, Valentina, Celi, Monica, Muscoli, Carolina, Ilari, Sara, Lauro, Filomena, Giancotti, Luigino Antonio, Morabito, Chiara, Feola, Maurizio, Tarantino, Umberto, Raffaeli, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738165/
https://www.ncbi.nlm.nih.gov/pubmed/29258584
http://dx.doi.org/10.1186/s13063-017-2363-z

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